ISSN: 1859 - 2872
Preliminary results of high-resolution manometry in diagnosis and classification for achalasia
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Abstract
Summary
Objective: To initially evaluate the diagnosis results and classification of achalasia on high-resolution manometry (HRM). Subject and method: A case-series on patients diagnosed with achalasia using upper gastrointestinal endoscopy or barium study, clinical severity using the Eckardt’s score before and after treatment, and HRM results according to the Chicago Classification 3.0. Result: Between April and December 2018, 20 patients were recruited (7 males and 13 females, the mean age 35.9 ± 15.4 years). The number of patients with achalasia type I, II, and III, and absent contractility were 2, 12, 2, and 4, respectively. The Eckardt’s score were not different between achalasia and absent contractility patients. The mean integrated relaxation pressure of LES (IRP4s) in achalasia patients was 24.6 ± 6.3mmHg and was not different among types. The Eckardt’s score before and after treatment in achalasia patients were 6.8 ± 2.8 and 2.1 ± 1.9, respectively (p<0.05). After treatment, two patients had normalized IRP4s but absent contractility (1 patient) and distal esophageal spasm (1 patient). Conclusion: HRM is valuable in diagnosis, classification, and treatment monitoring in achalasia.
Keywords: Achalasia, high-resolution esophageal manometry.
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References
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