Evaluate the post-operative analgesic effect of intrathecal morphine 0,2mg combined with postoperative IV-PCA in upper abdominal surgery

  • Đào Khắc Hùng Bệnh viện Đa khoa tỉnh Bắc Ninh

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Keywords

Post-operative analgesic, morphine, Patient - Controlled Analgesia (PCA), upper abdominal cavity

Abstract

Objective:  To evaluate the postoperative analgesic effect 0.2mg of morphine combined in to spinal cord with IV-PCA after surgery on the upper abdominal cavity. Subject and method: The study on 120 patients, scheduled operations on the upper abdomen, was divided into 2 groups: Group 1: Intravenous morphine PCA alone (bolus 1mg/ml; lockout time 5 minutes; limited dose 10mg/h). Group 2: Combined the method of injecting 200mcg of morphine in to spinal cord with IV-PCA (bolus 1mg/ml; lockout time 5 minutes; limited dose 10mg/h). Result and conclusion: VAS score at rest and move in to group 2 lower than group 1 from post-operative until 64 hours, the consumption of morphine for approve group 1 is 6.18 ± 2.21mg higher than group 2 is 4.38 ± 2.37mg and post-operative analgesia effective in the first 72 hours, group 1 is 55.4 ± 26.29mg higher group 2 is 34.1 ± 23.56mg and there is a difference between the two groups the value p<0.05. Side effects such as sedation level, nausea, vomiting, pruritus, urinary retention is no difference.

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References

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