Liên quan giữa lâm sàng, xét nghiệm với độ xơ hóa gan và giá trị của một số phương pháp chẩn đoán xơ hóa gan không xâm lấn trong bệnh gan nhiễm mỡ

Abstract

Objective: To assess the relationship of some clinical, biochemical factors to liver fibrosis and the value of some noninvasive methods for diagnosis of liver fibrosis. Subject and method: A cross-sectional study of 102 patients with liver fatty disease diagnosed by liver biopsy and histopathological examination. Result and conclusion: BMI and abdominal circumference were risk factors that were related to the degree of liver fibrosis. Serum AST, GGT were positively correlated with the degree of liver fibrosis; platelet, prothrombin ratio was inversely correlated with the degree of liver fibrosis. APRI, FIB4, Forns had a high value in the diagnosis of cirrhosis and advanced liver fibrosis (F₃ - F₄) in fatty liver disease, and had moderate value in the diagnosis of mild and moderate liver fibrosis (F₁ - F₂), without diagnosis early liver fibrosis.