The efficacy and safety of mechanical thrombectomy in acute basilar artery occlusion

  • Dinh Thi Hai Ha 108 Military Central Hospital

Main Article Content

Keywords

Acute basilar artery occlusion, revascularization, ischemic stroke

Tóm tắt

Objective: To evaluate the efficacy and safety of mechanical thrombectomy in revascularization of patients with acute basilar artery occlusion (ABAO). Subject and method: This study included 22 patients with acute ischemic stroke attributable to ABAO treated within the first 12 hours after onset of symptoms. The clinical outcome and mortality rate were assessed 180 days after treatment. Result: The mean ± SD age of the patients was 66.14 ± 14.37 years (range: 29 - 86 years), the mean NIHSS on admission was 21.86 ± 9.05 (range: 2 - 35) and the mean GCS was 10.36 ± 3.58 (range: 5 - 15). None patients simultaneously received intravenous thrombolysis. A favorable outcome, defined as a modified Rankin Score (mRS) of 0 - 2 was observed in 31.8% of patients (7/22). Overall mortality rate was 40.9% (9/22). No symptomatic intracerebral hemorrhages and no procedure-related complications occurred. Conclusion: Mechanical thrombectomy with the stent retriever device can rapidly and improve functional outcome in patients with ABAO and these strategies have a low incidence of complications.


Keywords: Acute basilar artery occlusion, revascularization, ischemic stroke.




Article Details

Các tài liệu tham khảo

1. Espinosa de Rueda M, Parrilla G, Zamarro J et al (2013) Treatment of acute vertebrobasilar occlusion using thrombectomy with stent retrievers: Initial experience with 18 patients. AJNR Am J Neuroradiol 34: 1044-1048.
2. Mourand I, Machi P, Milhaud D et al (2014) Mechanical thrombectomy with the solitaire device in acute basilar artery occlusion. J NeurointerventSurg 6: 200-204.
3. Vergouwen MD, Algra A, Pfefferkorn T et al (2012) Time is brain (stem) in basilar artery occlusion. Stroke 43: 3003-3006.
4. Yoon W, Park MS, Cho KH (2010) Low-dose intra-arterial urokinase and aggressive mechanical clot disruption for acute ischemic stroke after failure of intravenous thrombolysis. AJNR Am J Neuroradiol 31: 161-164.
5. Higashida RT, Furlan AJ, Roberts H et al (2003) Trial design and reporting standards for intra-arterial cerebral thrombolysis for acute ischemic stroke. Stroke 34: 109-137.
6. Smith WS (2007) Intra-arterial thrombolytic therapy for acute basilar artery occlusion: Pro. Stroke 38: 701-703.
7. Jung S, Mono ML, Fischer U et al (2011) Three-month and long-term outcomes and their predictors in acute basilar artery occlusion treated with intra-arterial thrombolysis. Stroke 42: 1946-1951.
8. Strbian D, Sairanen T, Silvennoinen H et al (2013) Thrombolysis of basilarartery occlusion: impact of baseline ischemia and time. Ann Neurol 73: 688-694.
9. Baek JM, Yoon W, Kim SK et al (2014) Acute basilar artery occlusion: Outcome of mechanical thrombectomy with solitaire stent within 8 hours of stroke onset. AJNR Am J Neuroradiol 35: 989-993.