Outcome of pancreaticoduodenectomy with standard lymphadenectomy in treatment of tumors in panceatic head area
Main Article Content
Keywords
Abstract
Objective: To evaluate the outcome of standard lymphadenectomy during pancreaticoduodenectomy in treatment patients with tumors in pancreatic-head area. Subject and method: A prospective, descriptive study on 173 patients who underwent pancreaticoduodenectomy with standard lymphadenectomy for tumors in pancreatic head area from July 2015 to July 2020 in 108 Military Central Hospital. Result: The average age was 60.3 ± 8 years, jaundice was the most common symptom (82.7%), histological showed 14.6% benign lesions, the average number of lympho node dissected was 12.9 ± 5.2, lympho node metastasis rate was 44.7%. The average operative time was 229.4 ± 42.5 minutes, mortality rate was 3.5% and postoperative hospital stay was 14.9 ± 6.5 days. Major complications included: Pancreatic fistula (20.8%), intraluminal bleeding (13.9%), abdominal cavity bleeding (9.2%) and delayed gastic emptying (8.1%). The average survival time was 36 months and the 3, 5-years overall survival rates were 42.2%, 38.9% respectively. Conclusion: Standard lymphadenectomy during pancreaticoduodenectomy is safe and effective procedure in treatment of lesions in pancreatic-head area
Article Details
References
2. William AR and Mike MB (2004) Evaluation and management of periampullary tumors. Current gastroenterology reports 6(5): 362.
3. Sherko A, Molah K et al (2018) The outcomes and complications of pancreaticoduodenectomy (Whipple procedure): Cross sectional study. International Journal of Surgery, 52: p. 383-387.
4. Hazem Z et al (2020) Prognostic factors for long-term survival after pancreaticoduodenectomy for periampullary adenocarcinoma. A retrospective cohort study. Annals of Medicine and Surgery.
5. Claudio B et al (2017) The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 Years After. Surgery 161(3): 584-591.
6. Porta M, Fabregat X, Malats N et al (2005) Exocrine pancreatic cancer: symptoms at presentation and their relation to tumour site and stage. Clin Transl Oncol 7: 189.
7. Serrano PE et al (2015) Improved long-term outcomes after resection of pancreatic adenocarcinoma: A comparison between two time periods. Annals of Surgical Oncology 22(4): 1160-1167.
8. Nguyễn Ngọc Bích (2009) Kết quả của phẫu thuật cắt đầu tụy tá tràng tại Khoa Ngoại Bệnh viện Bạch Mai. Tạp chí Y học Thực hành (667), số 7/2009.
9. Zakaria H et al (2020) Prognostic factors for long-term survival after pancreaticoduodenectomy for periampullary adenocarcinoma. A retrospective cohort study. Annals of Medicine and Surgery.
10. Kang JS et al (2020) Short- and long-term outcomes of pancreaticoduodenectomy in elderly patients with periampullary cancer. Ann Surg Treat Res 98(1): 7-14.