ISSN: 1859 - 2872
Clinical and paraclinical characteristics in patients with maligant biliary obstruction
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Abstract
Objective: To describe clinical and paraclinical features of malignant biliary obstruction patients. Subject and method: A prospective descriptive study, 88 inpatients suffering from malignant biliary obstruction who were undergone ERCP biliary stenting at the Department of Gastroenterology, 108 Military Central Hospital from 10/2014 to 10/2018. Result: Mean age was 62.4 ± 12.2 years. Common clinical symptoms included jaundice, anorexia, weight loss, abdominal pain and pruritus with rates 100.0%, 94.3%, 89.8%, 83.0% and 63.6%, respetively. Serum total bilirubin level was 315.1 ± 133.4 (µmol/l). 88/88 (100.0%) patients had bilateral intrahepatic bile duct dilation. The rate of distal and hilar obstruction were 55.7% and 44.3% respectively. Two dimension mean size of tumors which directly caused biliary obstruction and the mean length of obstructed bile duct were 43.8 ± 31.7/28.2 ± 8.9mm and 28.2 ± 8.9mm. Common causes of obstruction were pancreatic, extrahepatic bile duct, liver and intrahepatic cancers with correspoding rates 31.8%, 37.5%, 10.2% and 9.1%. TNM stage I, II, III and IV accounted for 10.2%, 30.7%, 17.0% and 42.0%, respectively. Conclusion: Majority of malignant biliary obstruction patients was middle age and elderly. Common clinical symptoms included jaundice, anorexia, weight loss, abdominal pain and pruritus with deteriorated overall condition. High total bilirubin level in the serum with image of the tumor that blocked bile duct. Main causes of obstruction were pancreatic, extrahepatic bile duct cancers.
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References
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