ISSN: 1859 - 2872
Non-adherence to chemotherapy medications and non-adherence-related factors among outpatients with hepatocellular carcinoma at 108 Military Central Hospital
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Abstract
Objective: To evaluate status of non-adherence to chemotherapy medications and non-adherence-related factors on outpatients with hepatocellular carcinoma (HCC) at 108 Military Central Hospital from January to May, 2021. Subject and method: A cross-sectional study was conducted on 184 over-18-years old outpatients with HCC. Chemotherapy non-adherence was determined via the eight-item Morisky Medication Adherence Scale. We measured five non-adherence-related factors included: Condition-related, patient-related, socio-economic-related, treatment-related and healthcare-system/provider-related factors. Result: The rate of chemotherapy non-adherence patients was 58.2%. Chemotherapy non-adherence-related factors included side effects of medications: Fatigue (p=0.011), nausea and vomiting (p=0.0001), pain (p=0.024), insomnia (p=0.018), hand-foot syndrome (p=0.025), diarrhea (p=0.002); diminished sense of priority for medication (p=0.04), concern about side effects (p=0.001) and level of trust indoctors (p=0.0001). Conclusion: 58.2% of HCC outpatients were chemotherapy non-adherence. The chemotherapy non-adherence-related factors were side effects of medications, concern about side effects, diminished sense of priority for medication and level of trust indoctors.
Keywords: Hepatocellular carcinoma, medication adherence, outpatients.
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References
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