Clinical, paraclinical and echocardiographic features in patients with partial atrioventricular septal defect

  • An Tran Thi Hanoi Heart Hospital
  • Son Pham Nguyen 108 Millitary Central Hospital

Main Article Content

Keywords

Atrioventricular septal defect, partial atrioventricular septal defect, echocardiography

Abstract

Objective: To evaluate the clinical, paraclinical and echocardiographic features in patients with partial atrioventricular septal defect (AVSD). Subject and method: A descriptive study, from January 2011 to December 2014, recruited 67 patients with partial transplantation having indication of surgery at Hanoi Heart Hospital. Result: The median age was 16 years (male/ female ratio: 1/1.16), of which 49.3% were over 16 years of age. There were 18 patients (26.9%) without obvious presentation and accidentally discovered the disease. The most common functional sign was dyspnea with NYHA II (56.7%). Physical signs included systolic murmur at apex of 88.1% and systolic murmur at left sternal border of 53.7%. 94% of patients had chest X-rays with a cardiothoracic index of ≥ 50%, and the signs of pulmonary hypertension of 49.3%. On electrocardiography, the main rhythms were sinus (91%), atrial fibrillation (7.5%) and complete atrioventricular block (1.5%). The left axis accounted for 62.7%, incomplete right bundle branch block of 67.2% and first degree atrioventricular block of 32.8%. On echocardiography, the primary lesions of partial AVSD were suitably described as in literature such as a large primary atrial septal defect (100%), mitral cleft (97%), left ventricular inlet/outlet ratio 1.2. However, the role of echocardiography in detailed diagnosis of mitral and tricuspid valve lesions was not high. Conclusion: The patients in our study had an average age was relatively high and nearly 27% were found accidentally. The majority of patients had typical clinical symptoms and paraclinical features in electrocardiography and echocardiography.


 

Article Details

References

1. Nguyễn Thị Mai Ngọc (2010) Đánh giá sức cản động mạch phổi bằng siêu âm Doppler tim trước và sau điều trị đóng lỗ thông liên nhĩ. Luận án Tiến sĩ Y học, Trường Đại học Y Hà Nội, Hà Nội.
2. Nguyễn Thị Thu Thủy (2016) Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và siêu âm tim ở bệnh nhân Ebstein. Luận văn Tiến sĩ Y học, Viện Nghiên cứu Khoa học Y Dược Lâm sàng 108, Hà Nội.
3. Đào Quang Vinh (2015) Nghiên cứu đánh giá kết quả điều trị phẫu thuật thông vách nhĩ thất bán phần. Luận án Tiến sĩ Y học, Học viện Quân y, Hà Nội.
4. Phạm Nguyễn Vinh (1999) Kênh nhĩ thất, trong siêu âm tim và bệnh lý tim mạch. Phạm Nguyễn Vinh (Chủ biên), tập 1, Nhà xuất bản Y học, Thành phố Hồ Chí Minh, chương 7, tr. 79-90.
5. Aubert S, Henaine R, Raisky O et al (2005) Atypical forms of isolated partial atrioventricular septal defect increase the risk of initial valve replacement and reoperation. Eur J Cardiothorac Surg 28(2): 223-228.
6. Backer CL and Mavroudis C (2003) Atrioventricular canal defects in (Eds), Pediatric cardiac surgery 3rd edition. Mosby, Philadelphia, chapter 18: 321-338.
7. Batisse A (2002) Canal atrioventriculaire (CAV) in Cardiologie pédiatrique pratique 2nd edition. Doin, Belin: 53-59.
8. El-Najdawi EK, Driscoll DJ, Puga FJ et al (2000) Operation for partial atrioventricular septal defect: A forty-year review. J Thorac Cardiovasc Surg 119(5): 880-889, discussion 889-890.
9. Gatzoulis MA, Hechter S, Webb GD et al (1999) Surgery for partial atrioventricular septal defect in the adult. Ann Thorac Surg 67(2): 504-510.
10. Najm H K, Williams WG, Chuaratanaphong S et al (1998) Primum atrial septal defect in children: Early results, risk factors, and freedom from reoperation. Ann Thorac Surg 66(3): 829-835.
11. O' Sullivan KE, Fleck R, Vigano G et al (2018) Long-term outcomes following partial atrioventricular septal defect (AVSD) repair in Ireland. Ir J Med Sci: 1-5.
12. Rice K and Simpson J (2015) Three-dimensional echocardiography of congenital abnormalities of the left atrioventricular valve. Echo Res Pract 2(1): 13-24.
13. Shinebourne EA and Ho SY (2003) Atrioventricular septal defect: Complete and partial (Ostium primum atrial septal defect). Gatzoulis MA, Webb GD, and Daubeney P.E.F. (Eds). Diagnosis and management of adult congenital heart disease. Churchill Livinstone, London 21: 179-187.
14. Waqar T, Riaz MU and Shuaib M (2017) Surgical repair of partial atrioventricular septal defect. Pak J Med Sci 33(2): 285-289