ISSN: 1859 - 2872
Clinical characteristics of the patients with chronic skin injuries after radiotherapy
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Abstract
Objective: Identifying clinical characteristics of cutaneous injuries in 30 patients after receiving radiotherapy. Subject and method: The cross-sectional study was conducted on 30 patients with skin lesions caused by radiation after their treatment at National Institute of Burns Le Huu Trac from October 2013 to September 2017. The selection criteria: Reasons for radiation treatment, radiation location, complications. Result: 30 patients comprised 5 (16.7%) males and 25 (83.3%) females completed the study. The mean age was 49.96 ± 18.52. The mean time of injury is 9 years and 8 months, the latest cutaneous radiation injury (CRI) occurred more than 31 years later. Patients with chronic phase: 100% and third degree of injury with rate of 50%. Conclusion: Skin lesions after radiation therapy is quite special, they appear immediately after radiation therapy, but clinically found in the chronic phases with long term chronic ischemia, high infection rates, more severe complications.
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References
2. Corinne D, Ralph D (1998) Functional assessment of cutaneous microvasculature after radiation. Radiotherapy and Oncology 51: 67-70.
3. Erica BC and Monique NM (2001) Acute effects of radiation treatment: Skin reactions. The Canadian Veterinary Journal 47(9): 931-935.
4. Gillette EL, LaRue SM, Gillette SM (1995) Normal tissue tolerance and management of radiation injury. Semin Vet Med Surg (Small Anim) 10(3): 209-213.
5. Heather C (2005) Wound healing perspectives. National healing corporation: 5-8.
6. Krizek TJ (1979) Difficult wounds: Radiation wounds. Clin Plast Surg 6(4): 541-543.
7. Mendelsohn (2002) Wound care after radiation therapy. Adv skin wound care 15: 216-224.
8. Splittle OBE (2009) High dose radiation effect and tissue injury. Health Protection Agency 2009 (except Appendix A of Chapter 5).
9. Marie-Gabrielle D, Florent de V (2004) Cancer mortality after radiotherapy for a skin hemangioma during childhood. Radiotherapy and Oncology 72: 87-93.
10. Richard PH, Asif Z, Javed M, Salomeh J, (2011) Investigations into the role of inflammation in normal tissue response to irradiation. Radiotherapy and Oncology 12(4): 25-32.
11. Siemionow, Maria, Mee, Jared (1999) Effects of 8-Gy radiation on the microcirculation of muscle flaps in the rat. Plastic & Reconstructive Surgery 104(5): 1372-1378.
12. Solange MA (2007) Effect of low-dose electron radiation on rat. Skin Wound Healing, BrazDent J 18(3): 208-214.
13. Sylvie D, Balla-Mekias S, Jean-Louis L (1999) Striking regression of chronic radiotherapy damage in a clinical trial of combined pentoxifylline and tocopherol. Journal of Clinical Oncology 17(10): 3283-3290.
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