ISSN: 1859 - 2872
The variation of serum concentration of IL-6, IL-10 in polytrauma patients with sepsis complication
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Abstract
Summary
Objective: To investigate the variation of serum concentration of IL-6, IL-10 in polytrauma patients with sepsis complication and associate with injury severity. Subject and method: Injury severity and multiple trauma patients’ status were assessed by ISS and RTS score. The level of IL-6, IL-10 were accessed at admision, 6, 12, 24, 48, 72 hours after trauma. Result: There were 20.9% of patients had sepsis complication. IL-6, IL-10 concentration increased soon after trauma. IL-6 concentration and IL-6/IL-10 ratio of group with sepsis complication was significant higher than that of group without sepsis complication. Conclusion: IL-6, IL-10 concentration increased soon after trauma in polytrauma patients. IL-6 level increased significantly in the first day, IL-10 level increased and had a maximum value at 3 days after trauma. IL-6 concentration and IL-6/IL-10 ratio of group with sepsis complication was significant higher than group without sepsis complication.
Keywords: Polytrauma, IL-6, IL-10, sepsis.
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References
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