Đặc điểm lâm sàng và các yếu tố liên quan ở bệnh nhân vảy nến có hội chứng chuyển hóa

Abstract

Objective: To describe the clinical features of psoriasis patients with metabolic syndrome, to determine psoriasis-related factors in patients with metabolic syndrome. Subject and method: Cross-sectional descriptive study. Eighty-five psoriasis patients with metabolic syndrome visited to Ho Chi Minh City Dermatology Hospital from 2016 to 2018. Result: The proportion of males is higher than females (70.6% and 29.4%, respectively). The mean age of patients with psoriasis was 51.5 ± 11.3 years. The average duration of psoriasis was 12.1 ± 8.7 years. Of psoriasis the patients, 11.7% had the psoriasis history from their mother. The mean BMI of psoriasis patients with metabolic syndrome was 22.8 ± 3.9. The BSA score in psoriasis patients with metabolic syndrome was 36.4 ± 22.3, in which patients with BSA classified as severe were 54.1%; the PASI score for psoriasis patients with metabolic syndrome was 25.2 ± 15.3, in which patients with PASI severity accounted for 48.2%. Among risk factors, the psorasis patients with occupational exposure to BSA show the metabolic syndrome (p<0.05). Among psoriasis patients with metabolic syndrome, 57.6% of patients with hypertension; 9.4% of patients with impaired glucose tolerance (IGT). The prevalence of dyslipidemia varied among groups of disorders: Hypercholesterolemia accounted for 43.5%; hypertriglyceridemia accounted for 51.7%; LDL-cholesterol increased by 34.1% and HDL-cholesterol decreased by 50.1%. Conclusion: The mean age of psoriasis patients with metabolic syndrome was high. Occupations were found to have signifimcant effect on the psoriasis status in patients with metabolic syndrome. Psoriasis might be affected by metabolic syndrome.