ISSN: 1859 - 2872
The predictors of overall survival time after surgical treatment in non-small cell lung cancer
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Abstract
Objective: To identify the prognostic factors in non-small cell lung cancer treated by combination surgery and adjuvant chemo-radiotherapy. Subject and method: Prospective, longitudinal description, 109 cases of primary non-small cell lung cancer were treated by VATS lobectomy and lymphadenectomy at University Medical Center Ho Chi Minh city and Pham Ngoc Thach Hospital from 01/01/2012 to 31/12/2016. Result: Total survival time was 46.9 ± 1.9 months (13 - 60 months); 100% survival rate in the first year; after 2 years 85.9%, after 3 years 65.3% and 5 year overall survival rate 55.9%. The postoperative stage of lung cancer and the ability of radical lymphadenectomy were significant factors in survival (p=0.001). In addition, the number of metastatic nodules, lymph node size (p<0.001), tumor size and tumor differentiation (p<0.05) were also predictors. Conclusion: Stage of lung cancer, surgical removal of radical lymph nodes, number of metastatic lymph nodes, size of lymph nodes, tumor differentiation and tumor size are predictive factors of postoperative survival in non-small cell lung cancer.
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