ISSN: 1859 - 2872
The relationship between plasma levels of hs-CRP and some clinical and subclinical characteristics in patients with type 2 diabetes
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Summary
Objective: To investigate the relationship between plasma levels of hs-CRP with some clinical and subclinical characteristics of type 2 diabetic patients treated at 175 Military Hospital. Subject and method: A cross-sectional descriptive study was conducted on 118 patients with type 2 diabetes. They were treated at 175 Military Hospital from April 2018 to March 2019. Result: Plasma concentrations of hs-CRP had a low positive correlation significantly with age (r = 0.256, p<0.01), and BMI (r = 0.233, p<0.05). At the same time, plasma hs-CRP concentrations had a low negative correlation significantly with HDL-C (r = -0.29, p<0.05). The average concentration of Hs-CRP plasma gradually increased with the number of risk factors, in which the patients had 4 risk factors with the highest average plasma hs-CRP level with 12.16 ± 32.85mg/L, the group with 1 risk factor was the lowest with 2.61 ± 4.68mg/L, this difference was not statistically significant with p>0.05. Increased hs-CRP had an independent association with positive protein, protein risk factors with OR = 6.282, p<0.05. The mean concentration of hs-CRP plasma between blood cholesterol groups according to treatment goals (good, accepted, poor) was significantly different with p<0.05. Conclusion: Plasma concentrations of hs-CRP have a low positive correlation with age and BMI, and a low inverse correlation with HDL-C. Increased hs-CRP has an independent association with positive urine protein. There were difference significantly in plasma hs-CRP concentrations between blood cholesterol groups according to treatment goals.
Keywords: High sensitivity reactive Protein C, cardiovascular risk factors, type 2 diabetes.
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References
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