ISSN: 1859 - 2872
Interleukin-8 in the serum of acne vulgaris patients in Dermato-Venereology Hospital of Ho Chi Minh City
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Abstract
Objective: To compare the concentration of interleukin-8 (IL-8) in the serum of acne vulgaris patients with the control group. Subject and method: Case-control study, 80 patients and 80 control groups in Dermato-Venereology Hospital of Ho Chi Minh City, from 11/2018 to 9/2019. Diagnosis of acne vulgaris is based on clinical findings and severity of the disease according to the Global Acne Classification System (GAGS). Quantification of serum concentration of IL-8 by ELISA method (Enzym - Linked Immunosorbent Assay) at the Center of Molecular Biomedicine of University of Medicine and Pharmacy in Ho Chi Minh City. Data are processed by Stata 14.2 software. Result: Our sample had a higher number of females than males, the average age was 23 ± 02 years, the youngest age was 19, the oldest was 29, serum concentration of IL-8 in acne patients had 22.05 ± 49.89pg/ml, control group had 6.24 ± 8.45pg/ml. The difference was statistically significant (p<0.001). There was a statistically significant relationship between serum concentration of IL-8 and severity of the disease (p<0.05). Conclusion: The serum concentration of IL-8 in acne group was higher than the control group, the difference was statistically significant (p<0.001); there was a statistically significant relationship between serum concentration of IL-8 and severity of the disease (p<0.05).
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