The study of coagulopathy in polytrauma patients and its correlation with injury severity

  • Nguyễn Trường Giang
  • Nguyễn Trung Kiên

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Keywords

Polytrauma, injury severity, coagulopathy

Abstract

Summary


Objective: To evaluate the correlation between coagulopathy with injury severity in polytrauma patients. Subject and method: Injury severity of multiple trauma patients were assessed by ISS and RTS score. The level of PT, aPTT time, platelet, and fibrinogen concentration were measured at the time of admision (T0), 6 (T1), 12 (T2), 24 (T3), 48 (T4) and 72 (T5) hours after trauma. Result: There were 46.67% of patients had a coagulopathy with the changes of PT, aPTT, concentration of fibrinogen early after trauma. ISS of group with coagulopathy (36.64 ± 12.82) was significant higher than that of group with non-coagulopathy (32.16 ± 11.18) with p<0.05. At the time of admittance, PT, aPTT and fibrinogen related to injury severity with ISS score (r = 0.295, r = 0.256 and r = 0.527, p=0.000) and RTS score (r = 0.245, r = 0.285 and r = 0.457, p=0.000). Conclusion: Coagulopathy happened right after initial hours of trauma and continued through out 1 - 2 days after trauma. There was a correlation between PT, concentration of fibrinogen with injury severity by ISS or RTS in polytrauma patients.  


Keywords: Polytrauma, injury severity, coagulopathy.

Article Details

References

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Published
Apr 4, 2020
Issue
Volume 15 - No 4/2020
Section
Articles
How to Cite
Trường GiangN., & Trung KiênN. (2020). The study of coagulopathy in polytrauma patients and its correlation with injury severity . Tạp Chí Y Dược lâm sàng 108, 15(4). Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/354