Study on the effectiveness of GTK 108 formula in treatment for chronic skin ulcer on experimental animals

  • Nguyễn Thu Trang
  • Đỗ Thuý Hằng
  • Lương Thị Kỳ Thuỷ
  • Phạm Xuân Thắng
  • Trần Quang Minh

Main Article Content

Keywords

Chronic ulcer, experimental animal, GTK 108

Abstract

Summary


Objective: To determine the prevelance of the GTK 108 formula as topical ulcer dressings on experimental animals. Subject and method: A experimental research on animals. Result: It showed that the chronic skin ulcers which were treated with GTK108 formula were healed faster than the controlled groups. The fully healed rate in study group was 100%. Conclusion: GTK108 formular was considered to be more effective than other topical applications in the treatment of chronic ulcers on experimental animals.


Keywords: Chronic ulcer, experimental animal, GTK 108.

Article Details

References

1. Lương Thị Kỳ Thủy, Lê Đình Roanh, Phạm Viết Dự và cộng sự (2014) Đánh giá tác dụng điều trị loét da mạn tính của cao TG trên mô hình thực nghiệm. Tạp Chí Dược Học Cổ Truyền Quân Sự, 4(2), tr. 15-22.
2. Frykberg RG and Banks J (2015) Challenges in the treatment of chronic wounds. Adv Wound Care 4(9): 560-582.
3. Sen CK, Gordillo GM, Roy S et al (2009) Human skin wounds: A mand snowballing threat to public health and the economy. Wound Repair Regen Off Publ Wound Heal Soc Eur Tissue Repair Soc 17(6): 763-771.
4. Li FL, Wang YF, Li X et al (2012) Characteristics and clinical managements of chronic skin ulcers based on traditional Chinese medicine. Evid Based Complement Alternat Med: 1-6.
5. Rudolph R, Woodward M, and Hurn I (1979) Ultrastructure of doxorubicin (Adriamycin)-induced skin ulcers in rats. Cancer Res 39(9): 3689-3693.
6. Sanada H, Moriguchi T, Miyachi Y et al. (2004) Reliability and validity of DESIGN, a tool that classifies pressure ulcer severity and monitors healing. J Wound Care 13(1): 13-18.