ISSN: 1859 - 2872
Long-term functional outcome and prognostic factors after neuronavigation-assisted neuroendoscopic evacuation for supratentorial spontaneous intracerebral hemorrhage
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Abstract
Objective: To evaluate long-term functional outcome and identify prognostic factors associated with poor functional outcome in patients with supratentorial spontaneous intracerebral hemorrhage undergoing neuronavigation-assisted neuroendoscopic evacuation at Military Hospital 103. Subject and method: A prospective, descriptive, uncontrolled study was conducted in 51 patients. Functional outcome was evaluated according to the modified Rankin Scale (mRS) at post-operative 6- and 12-months. Logistic regression analysis was performed to determine prognostic factors associated with functional outcome. Result: Poor functional outcome (mRS 4-6) were observed in 43.2% of patients at 6 months and 47.1% at 12 months postoperative follow-up. Factors associated with poor functional outcome included age ≥ 60 years, NIHSS score ≥16, ESSEN score ≥ 6, and the third day postoperative fever. Multivariable logistic regression identified ESSEN score ≥ 6 (OR = 0.148, p=0.006) and hematoma evacuation rate (OR = 0.934, p=0.048) as independent prognostic factors. Conclusion: Long-term functional outcome was primarily determined by admission neurological characteristics and the hematoma evacuation rate.
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References
2. Greenberg SM, Dowlatshahi D, Hemphill JC et al (2022) Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association. Stroke 53: 282-361.
3. Zhi Zhonghua Yi Xue Za (2024) [Chinese expert consensus on surgical treatment of hypertensive intracerebral hemorrhage based on parafascicular approach(2024 edition)]. Zhonghua Yi Xue Za Zhi, 104(33): 3096-3109.
4. Arthur AS, Jahromi BS, Saphier PS et al (2025) Minimally Invasive Surgery vs Medical Management Alone for Intracerebral Hemorrhage: The MIND Randomized Clinical Trial. JAMA Neurol 82(11): 1113-1121.
5. Ali M, Zhang X, Ascanio LC et al (2023) Long-term functional independence after minimally invasive endoscopic intracerebral hemorrhage evacuation. J Neurosurg 138(1): 154-164.
6. Kellner CP, Song R, Pan J et al (2020) Long-term functional outcome following minimally invasive endoscopic intracerebral hemorrhage evacuation. J Neurointerv Surg 12(5): 489-494.
7. Kellner CP, Chartrain AG, Ormseth CH (2021) Time to Evacuation and Functional Outcome After Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation. Stroke 52(10): 3100-3108.
8. Guo C, Bai Y, Zhang X et al (2025) Long-term efficacy and safety of endoscopic surgery versus small bone window craniotomy for spontaneous supratentorial intracerebral hemorrhage: A meta-analysis and trial sequential analysis. BMC Neurol, 25(1): 55.
9. Hanley DF, Rosenblum M, Yenokyan G et al (2019) Minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): a randomised, controlled, open-label phase 3 trial with blinded endpoint. The Lancet 393(10175): 1021–1032.
10. Ziai WC, Yarava A, Gruber JB et al (2026) Impact of Minimally Invasive Surgery on Midline Shift and Outcomes in Large Supratentorial Spontaneous Intracerebral Hemorrhage: Post Hoc Analysis of MISTIE III. Neurocrit Care 44(1): 261-272.
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