ISSN: 1859 - 2872
Helicobacter pylori infection and relationship with portal hypertensive gastropathy in patients with cirrhosis
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Abstract
Objective: To determine the prevalence of Helicobarter pylori (H. pylori) infection and evaluate relationship between H. pylori infection and portal hypertensive gastropathy (PHG) in cirrhotic patients. Subject and method: Prospective, cross-sectional descriptive study carried out on 65 patients with cirrhosis in Digestive Department of 103 Military Hospital. The diagnosis and determination of degree of PHG were based on the Baveno III consensus workshop. The severity of H. pylori infection was evaluated by histopathological method. Result: Prevalence of PHG and H. pylori infection in cirrhotic patients was 67.7% and 47.7%, respectively, in which mainly mild degree H. pylori infection (22/31 = 71.0%). There is insignificant association between H. pylori infection and the degree of liver dysfunction according to Child-Pugh classification, as well the occurrence and severity of PHG in patients with cirrhosis. Conclusion: H. pylori infection is unlikely to be involved in the pathogenesis of PHG.
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References
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