ISSN: 1859 - 2872
Biochemical indicators associated with metabolic disorders during the first six months after kidney transplantation at 108 Military Central Hospital
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Abstract
Objective: To describe metabolic disorders and associated factors during the first 6 months post-kidney transplantation at the 108 Military Central Hospital. Methods: A retrospective longitudinal cohort study was conducted on 131 kidney transplant recipients. Anthropometric and biochemical parameters were collected pre-transplantation and followed up for at least 6 months post-surgery. Results: Pre-transplantation, 56.5% of patients had a normal BMI, while 20.6% were underweight (BMI < 18.5kg/m²). The prevalence of patients with at least one pre-transplant metabolic disorder was 63.4%, with dyslipidemia and hyperuricemia accounting for 45.0% and 29.8%, respectively. Post-transplantation, the rate of hyperglycemia increased significantly at 1 month (23.7%) compared to baseline, followed by a gradual decline. Hypertriglyceridemia emerged as the most common lipid abnormality, particularly during the early post-transplant phase. Analysis of associated factors revealed that pre-transplant BMI statistically influenced metabolic disorders at 3 months post-transplantation (p<0.05). Conclusion: Metabolic disorders are highly prevalent among kidney transplant recipients, particularly in the early post-transplant period. Routine monitoring of metabolic indicators, enhanced nutritional counseling, and lifestyle modifications are essential for these patients.
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References
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