Nghiên cứu một số đặc điểm cận lâm sàng ở trẻ em bị dị ứng thức ăn

Abstract

Objective: To describe the pediatric allergy clinical characteristics of pediatric patients treated at the Vietnam National Children’s Hospital from June 2014 to June 2015. Subject and method: A cross-sectional descriptive study of 86 pediatric patients food allergy treatment in the Immunology - Allergies Department was selected in the study. Skin prick testing, skin patch test, stimulant stimulation test, eosinophils in blood, elevated total IgE and elevated specific IgE is performed. Result: The rate of skin prick test and skin patch test positive for cow's milk protein was highest (73.3% and 89.5%), followed by shrimp (15.1% and 15.8%), crabs (11.6%), beef (10.5%), egg white (8.1%), the rate of skin prick test positive in the ≥ 6 months group was 25.5%, higher than the < 6 months group was 5.1% (p<0.05). Eosin accounted > 4% for 32.4%, red blood cell in stool accounted for 42.9%, total IgE is higher than 230IU/ml, accounting for 19.0%. Specific IgE increased with cow's milk protein (beta lactoglobuline and casein); the rate of susceptibility to beef was 17.5%, in which the susceptibility was 6.4%; high susceptibility rate with egg yolk 1.6%. Conclusion: Some invivo and in vitro can support for the diagnosis of food allergies, such as: Skin test, skin-to-skin tests or IgE-specific test. However, the diagnosis of food allergies is especially challenging for children.