Results of liver transplantation for hepatocellular carcinoma in Viet Duc University Hospital

  • Nguyễn Tiến Quyết Trung tâm ghép tạng, Bệnh viện Hữu nghị Việt Đức
  • Nguyễn Quang Nghĩa Trung tâm ghép tạng, Bệnh viện Hữu nghị Việt Đức
  • Ninh Việt Khải Trung tâm ghép tạng, Bệnh viện Hữu nghị Việt Đức
  • Trần Minh Tuấn Trung tâm ghép tạng, Bệnh viện Hữu nghị Việt Đức
  • Đặng Kim Khuê Trung tâm ghép tạng, Bệnh viện Hữu nghị Việt Đức

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Keywords

Liver transplantation, hepatocellular carcinoma

Abstract

Objective: To evaluate the results of liver transplantation for hepatocellular carcinoma (HCC) patients at Viet Duc University Hospital. Subject and method: Prospective study of 24 HCC patients underwent liver transplantation at Viet Duc University Hospital from November 2007 to November 2016. Result: There are 22 male, 2 female patients with average age of 53 (38 - 74). 95.8% of the patients were with chronic hepatitis B. 54.2% were within Milan criteria, while 45.8% were exceeding Milan criteria, with average number of tumor were 2.8 (1 - 5), and average diameter of 43.9mm (13 - 84). Early results: Mortality rate is 12.5% (3 patients), morbidities including: Pleural effusion 75%, bleeding 8.3%, bile leakage 4.2%, hepatic artery thrombosis 4.2%, hepatic vein stenosis 4.2%. The overall 5-year survival rate is 70.8%. Conclusion: Liver transplantation is efficient to treat early staged HCC patients.

Article Details

References

1. Nguyễn Quang Nghĩa (2012) Nghiên cứu áp dụng đo thể tích gan bằng chụp cắt lớp vi tính trong chỉ định, điều trị phẫu thuật ung thư gan nguyên phát. Luận án Tiến sĩ y học, Học viện Quân y, Hà Nội.
2. Nguyễn Tiến Quyết (2013) Ghép gan người lớn. Sách chuyên khảo.
3. Clavien PA, Selzner M et al (1998) Liver transplantation complicated by misplaced TIPS in the portal vein. Ann Surg 227(3): 440-445.
4. Coelho GR, Leitao AS, Cavalcante FP et al (2008) Continuous versus interrupted suture for hepatic artery anastomosis in liver transplantation: Differences in the incidence of hepatic artery thrombosis. Transplant proc 40: 3545-3547.
5. Ishizaki Y, Kawasaki S (2008) The evolution of liver transplantation for hepatocellular carcinoma (past, present, and furture). J Gastroenterol 43: 18-26.
6. Gruttadauria, S, Vasta F et al (2005) Basiliximab in a triple-drug regimen with tacrolimus and steroids in liver transplantation. Transplant Proc 37(6): 2611-2613.
7. Liang, TB, Bai XL et al (2007) Early postoperative hemorrhage requiring urgent surgical reintervention after orthotopic liver transplantation. Transplant Proc 39(5): 1549-1553.
8. Mazzaferro et al (1996) Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 334: 693-699.
9. Millonig, G, Graziadei IW et al (2007) Response to preoperative chemoembolization correlates with outcome after liver transplantation in patients with hepatocellular carcinoma. Liver Transpl 13(2): 272-279.
10. Stange BJ, Glanemann M, Nuessler NC et al (2003) Hepatic artery thrombosis after adult liver transplantation. LiverTranspl 9: 612-620.

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Published
Apr 18, 2018
Issue
Volume 13 - No 2 /2018
Section
Articles
How to Cite
QuyếtN. T., NghĩaN. Q., KhảiN. V., TuấnT. M., & Khuê Đặng K. (2018). Results of liver transplantation for hepatocellular carcinoma in Viet Duc University Hospital. Tạp Chí Y Dược lâm sàng 108, 13(2). Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/288