Kiểm định giá trị cấu trúc và khả năng phân biệt của thang đo VQ11 đối với chất lượng cuộc sống người bệnh phổi tắc nghẽn mạn tính

Abstract

Objective: This study aimed to assess the construct validity and discriminative ability of the Vietnamese version of the VQ11 questionnaire in measuring quality of life among patients with chronic obstructive pulmonary disease (COPD). Subject and method: A cross-sectional study was conducted on 168 COPD patients at the respiratory outpatient clinic of Thanh Nhan Hospital from April to May 2025. Data were collected using the Vietnamese version of the VQ11 questionnaire through face-to-face interviews. Exploratory Factor Analysis (EFA) was performed to examine the underlying factor structure. Internal consistency was assessed using Cronbach’s alpha. Discriminative validity was evaluated by comparing VQ11 scores between clinical subgroups based on the degree of dyspnea (mMRC) and symptom severity (CAT score). Result: The KMO index was 0.935, and Bartlett’s test was statistically significant (p<0.001), indicating that the data were suitable for EFA. Two main factors were extracted, explaining 74.3% of the total variance. The items clearly clustered into two distinct components. The overall Cronbach’s alpha was 0.942, and all items had item-total correlations above 0.3. The median VQ11 score was higher in patients with mMRC ≥ 2 (28.5; IQR: 11) than in those with mMRC < 2 (21.0; IQR: 4); p<0.001. Similarly, patients with CAT ≥ 10 had higher VQ11 scores than those with CAT < 10 (23.0 vs. 20.0; p<0.001). Conclusion: The Vietnamese version of the VQ11 demonstrates a clear two-factor structure, high internal consistency, and good discriminative validity among COPD patients. It is a suitable tool for assessing quality of life in COPD populations in Vietnam.