Nghiên cứu một số đặc điểm và các mối liên quan về suy giảm nhận thức chung trên bệnh nhân động kinh cơn lớn là người trưởng thành

Abstract

Objective: The study was conducted to describe some clinical features and relevances of cognitive impairment in adult patients with grand mal seizure. Subject and method: 60 adult patients with grand mal seizure were evaluated by clinical examination and Mini Mental State Examination (MMSE score). Results: The mean MMSE score was 23.72 ± 5.04; 58% of patients had MMSE score < 25. There were no significant difference in MMSE score between gender, age group and disease duration (p>0.05). The mean MMSE score of patients using gardenal was 20.2 ± 4.64 lower than that of patients using other drug (24.42 ± 4.86). Conclusion: 58% of patients had congnitive impairment. There were no significant difference in cognitive impairment between genders, ages and disease duration in patients with grand mal seizure. Patients using phenobacbital (gardenal) had higher rate of congnitve impairment than those using other antiepileptic drugs.