ISSN: 1859 - 2872
Plasma iron concentration changes in mortality prognosis in patients with sepsis
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Abstract
Objective: To determine the change in plasma iron level in patients with sepsis and the degree of change in iron level (∆ iron) in predicting 30-day mortality. Subject and method: Prospective descriptive study was conducted on 107 patients with sepsis treated at 108 Military Central Hospital from November 2019 to February 2021. Plasma iron levels were measured at the time of diagnosis and on day 3 after diagnosis made, 30-day follow-up of survival and mortality. Result: Plasma iron level at T1 was lower than that at T3 (1.7 (0.9 - 3.3) µmol/L and 6.2 (3.6 - 9.9) µmol/L (p<0.001)), respectively. Patients with ∆ iron < 2.65µmol/L had a higher risk of 30-day mortality than patients with ∆ iron ≥ 2.65µmol/L with RR and 95% CI of 3.86 (1.49 - 9.94), p<0.01. Conclusion: Change in plasma iron level may be a risk factor for 30-day mortality in patients with sepsis.
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References
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