Kết quả xạ trị giảm nhẹ ở bệnh nhân ung thư thực quản giai đoạn muộn tại Bệnh viện Trung ương Quân đội 108

Abstract

Objective: To assess the treatment response and survival rate of palliative radiotherapy in incurable esophageal cancer patients at 108 Military Central Hospital. Subject and method: A prospective descriptive study on 71 esophageal cancer patients stage III/IV underwent palliative radiotherapy 30Gy/10 fraction followed by chemotherapy or not. Treatment response, local control rate and survival rate were evaluated. Result: 49.3% patients received radiotherapy alone, 50.7% patients  underwent  radio-chemotherapy. The dysphagia improvement rate and weight gain rate at 3 months were 88.2% and 77.5%. Treament response on endoscopic: Complete response 31.0%, partial response 52.1%, non response 11.3%. The 1-year overall survival rate and 1-year local control rate were 20.3% and 24.4%. The median overall survival and median local control time of patients with radiotherapy alone and radio-chemotherapy were 7 and 8 months, 5 and 7 months, respectively (p>0.05). Ulceration and fistula were observed in 3 patients. Conclusion: Palliative radiotherapy leads to improve dysphagia and weight gain in incurable esophageal cancer patients. Tumor control treatment should be prefer in these patients.