Studying the role of respiratory resistance and reactance using forced oscillation technique in the diagnosis and stage classification of chronic obstructive pulmonary disease

  • Dong Nguyen Phuong 108 Military Central Hospital
  • Hau Luu Van 108 Military Central Hospital
  • Tien Nguyen Dinh 108 Military Central Hospital
  • Anh Dao Van 108 Military Central Hospital
  • Hai Nguyen Minh 108 Military Central Hospital

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Keywords

Respiratory resistance, reactance, chronic obstructive pulmonary disease

Abstract

Objective: To assess the role of respiratory resistance and reactance using forced oscillation technique in the diagnosis and stage classification of chronic obstructive pulmonary disease (COPD) patients. Subject and method: The study has been done in 108 Military Central Hospital from September 2017 to November 2018, among 200 COPD patients, included 150 stable COPD patients and 50 patients with COPD exacerbation. Al blood tests, blood gas, ECG, echography had done for 200 patients. Respiratory resistance (Rrs5 and Rrs20) and reactance (Xrs5) and pulmonary function tests were measured by MostGraph-02 (Chest M.I., Co. Ltd., Tokyo, Japan) in 150 stable COPD patients. For 50 patients with COPD exacerbation, only respiratory resistance (Rrs5 and Rrs20) and reactance (Xrs5) were measured. Result: Parameters of pulmonary function tests had been decreased: FVC: 2.81 ± 0.52L, FEV1: 1.85 ± 0.34L, FEV1%: 53.10 ± 22.90%, FEV1/FVC: 52.42 ± 10.65%, PEF 25-75 (%): 22.56 ± 13.82%, PEF: 24.37 ± 14.91%. Respiratory resistance Rrs5 and Rrs20 were higher and reactance Xrs more negative in exacerbations COPD patients than in stable COPD patients. Rrs5 has moderate inverse correlation with FEV1, FEV1% (-0.542 và -0.573) and tight inverse correlation (r = -0.61) with FEV1/FVC. Xrs5 has moderate positive correlation with FEV1, FEV1% and FEV1/FVC (r = 0.492, 0.512, 0.559). R5 and R20 increase in severity of disease, X5 decrease in severity of disease. Conclusion: Respiratory resistance and reactance have a role in the diagnosis and stage classification of COPD.


 

Article Details

References

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Published
Nov 29, 2020
Issue
Volume 14 - No 2/2019
Section
Articles
How to Cite
Nguyen PhuongD., Luu VanH., Nguyen DinhT., Dao VanA., & Nguyen MinhH. (2020). Studying the role of respiratory resistance and reactance using forced oscillation technique in the diagnosis and stage classification of chronic obstructive pulmonary disease. Tạp Chí Y Dược lâm sàng 108, 14(2), 51-57. Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/261