ISSN: 1859 - 2872
Study on the effectiveness of cytokine reduction of continuous veno-venous hemofiltration using oXiris filter in patients with septic shock
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Abstract
Objective: To assess the effectiveness of cytokine reduction of continuous veno-venous hemofiltration (CVVH) using oXiris membrane in patients with septic shock. Subject and method: 31 patients with septic shock treated at the Intensive Care Unit of Thu Duc Hospital, 115 Hospital and Bach Mai Hospital from January 2015 to April 2018. Method: Prospective, descriptive, cross-sectional study. Result: Of the 31 patients, 15 patients survived, accounting for 48.4% (group 1), 16 patients died, accounting for 51.6% (group 2). After continuous veno-venous hemofiltration, the concentration of cytokines decreased: TNF-α, IL-6, IL-8 decreased gradually, the difference was statistically significant starting from T2, IL-1b at T3 and IL-10 at T4. Conclusion: CVVH using oXiris filter results in reducing post-filtration cytokines.
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References
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