Evaluation of resuscitation for potential brain-dead pancreas donors at the 108 Military Central Hospital
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Abstract
Pancreas-kidney transplantation is the most effective treatment for patients with severe diabetes complicated by end-stage renal disease. Resuscitating brain-dead patients who are potential organ donors plays a critical role in creating a source of quality donor organs. Objective: To evaluate the outcomes of applying a resuscitation protocol for brain-dead potential organ donors at the 108 Military Central Hospital in pancreas-kidney transplantation. Subject and method: A prospective study of 15 brain-dead patients who were resuscitated for organ donation at the 108 Military Central Hospital from January 2023 to December 2023. Result: The average age was 35.5 years, with most in the working-age group. 84.6% were male, and 66.7% had experienced traffic accidents. In 100% of cases, cardiac function was preserved without structural changes. 77.2% required vasopressor support (noradrenaline). Pancreatic function: Blood glucose levels were maintained between 7.7-9.3mmol/L with an insulin dose of 6.7-11.3 IU/24h, pancreatic enzymes remained within normal limits, and kidney function along with daily urine output were within normal ranges. Conclusion: The resuscitation protocol for brain-dead potential organ donors is feasible and safe, providing an additional source of organs that meet the standards for pancreas-kidney transplantation in patients with severe diabetes and renal failure who are candidates for transplantation.
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References
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