Drug-related problems of statin use in outpatient type 2 diabetes at a tertiary hospital

  • Nguyễn Như Minh Trường Đại học Y khoa Phạm Ngọc Thạch
  • Nguyễn Liên Nhựt Bệnh viện Nguyễn Tri Phương
  • Phùng Xuân Đồng Bệnh viện Nguyễn Tri Phương
  • Đỗ Trần Khánh Vy Trường Đại học Y khoa Phạm Ngọc Thạch
  • Lê Phúc Như Quỳnh Trường Đại học Y khoa Phạm Ngọc Thạch
  • Võ Thị Hà Trường Đại học Dược Hà Nội
  • Võ Thị Hà Trường Đại học Dược Hà Nội

Main Article Content

Keywords

statin, Atherosclerotic cardiovascular disease, type 2 diabetes, drug-related problems

Abstract

Objective: We assessed drug-related problems (DPRs) of statins among type 2 diabetes outpatients at a tertiary hospital in Ho Chi Minh city. Subject and method: A cross-sectional study was conducted on 250 outpatients diagnosed with type 2 diabetes aged 40-75 years from February to April 2024 at Nguyen Tri Phuong Hospital. Data was collected from prescriptions, electronic records, and direct interview of patients to analyze DRPs using the ViMedÒ tool by clinical pharmacist, then approved by cardiologist. Result: The prescription rate of statins was 87.6% with moderate-intensity accounted for most of the sample (93.6%). The proportion of drug-related problems of statins was 57.2%. Treatment monitoring, dosage and missing indication were the major problem categories (55.5%, 20.8% and 16.2%). Rate of physicians’ acceptance was 96.5%. Patients with LDL-c > 2.5mmol/L were 2.2 times more likely to have statin drug problems (p=0.013). High-intensity users showed fewer drug problems (p<0.01). Conclusion: The utilization of statins remained suboptimal, especially in monitoring treatment, drug dosage and missing indication.

Article Details

References

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