Khảo sát mức độ hiểu biết và tuân thủ điều trị thuốc ức chế miễn dịch ở bệnh nhân sau ghép thận tại Bệnh viện Trung ương Quân đội 108

Abstract

Objective: To survey the knowledge and adherence to immunosuppressants among outpatient kidney transplant recipients at 108 Military Central Hospital and to determine the factors influencing these outcomes. Subject and method: A cross-sectional descriptive study was conducted using interviews with 94 kidney transplant patients. Patients' knowledge of immunosuppressant use was assessed using the Bertrams et al. questionnaire. Patients' adherence with using immunosuppressants was assessed using the BAASIS questionnaire. Boosting classification algorithm was applied to identify and assess the influence of factors affecting knowledge scores. BMA (Bayesian Model Averaging) method was used to build a model of factors influencing patient adherence. Result: The average knowledge score of patients was recorded as 6.0 ± 1.2 points. Knowledge score was associated with BK virus (BKV) infection at 26.16%, followed by information sources from the Internet and product information leaflets, contributing 19.73% and 18.59%, respectively. The adherence rate among patients was 76.6%. Patients with a post-transplant period of ≥ 2 years and knowledge score of < 6 points had the lower risk of adherence, with p=0.011 and p=0.046, respectively.  Conclusion: Most patients demonstrated high knowledge scores and good adherence to treatment. Those with a post-transplant period of more than 2 years and knowledge scores below 6 had lower adherence.