Khảo sát đặc điểm lâm sàng, cận lâm sàng và kết quả điều trị viêm nội tâm mạc nhiễm khuẩn do tụ cầu tại Bệnh viện Đại học Y Dược thành phố Hồ Chí Minh

Abstract

Objective: To describe the clinical and paraclinical characteristics and treatment outcomes of staphylococcal infective endocarditis. Subject and method: This prospective descriptive study, followed the outcomes at discharge of patients diagnosed with staphylococcal infective endocarditis at the University Medical Center Ho Chi Minh city from October 1, 2021 to May 20, 2024. Result: The study included 18 patients with a mean age of 54 ± 17.49 years, 61.1% of whom were male. The most common comorbidities were hypertension (55.6%) and valvular heart disease (44.4%). Fever was the most prevalent symptom (88.9%), followed by neurological symptoms (dizziness, weakness, headache). Blood cultures were positive for Staphylococcus aureus in 88.89% of cases. Vegetations were observed in all patients, with an average size of 13.78 ± 5.72mm, causing multiple intracardiac and extracardiac complications. The in-hospital mortality rate was 22.2%. Conclusion: Staphylococcal infective endocarditis presents with numerous nonspecific extracardiac symptoms and is difficult to diagnose. Echocardiography facilitates early diagnosis by detecting vegetations with high sensitivity and evaluating associated lesions. Staphylococcus aureus is the primary causative agent. The disease is associated with multiple complications and a high mortality rate.