ISSN: 1859 - 2872
Application of organ transplant resuscitation protocol for brain-dead potential donors: Outcome at 108 Military Central Hospital
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Abstract
Objective: To evaluate the outcome of organ transplant resuscitation protocol for brain-dead potential donors. Subject and method: Retrospective study of 30 brain-dead cases undergoing organ transplant resuscitation at 108 Military Central Hospital from 1/2020 to 12/2023. Result: The mean age was 32.91 years old, most were among working age, were dead due to traffic accidents. 90% were male. 100% had normal cardiac ejection fraction and structure, 77.2% required vasopressor (noradrenaline). 80% maintained PaO2 > 90mmHg, 2/30 (6,67%) were hypercapnia, well managed from post-mortem day 2. Kidney and liver function were within normal limit with increase in urine output: 9/21 (42.9%) > 1.5ml/h in day 3, suggesting diabetes insipidus. Glycemia was 9.24-10.37mmol/L, pancreatic enzymes were within normal limit. Rate of organs standardized for transplantation was 53.3% for kidney, 36.7% for liver, 46.7% for heart and 13.3% for lung. 2 cases became multi-organ donors, with 2 hearts, 4 lungs, 4 kidneys, 2 livers transplanted. Conclusion: Organ transplant resuscitation protocol for brain-dead potential donors were feasible, safe, and beneficial as an important resource for standardized organ for end-stage organ failure patients.
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References
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