ISSN: 1859 - 2872
Hospital infections and antibiotic resistance in pemphigus patients treated at Ho Chi Minh city Hospital of Dermato-Venereology
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Abstract
Objective: To survey the infective, nosocomical infection, bacteria, and antimicrobial resistance in pemphigus patients. Subject and method: The retrospective cross-sectional study involved 254 pemphigus patients hospitalized in Ho Chi Minh City Hospital of Dermato-Venereology from 1/1/2015 to 31/12/2017. The patient data about epidemiology, clinical nosocomial infection estimated according to the CDC 1996, bacteria and antibiogram... were collected from patient records. Result: From 2015 to 2017, in this sample, female outnumbered male, more than 3/4 patients living in provinces and pemphigus vulgaris was majority with 84.5%/2015, 82%/2016, 76.5%/2017. At least 98% pemphigus patients had infection at the hospitalised time. Infection from 2015 to 2017 S. aureus (36.3%, 50% và 53.7%), methicillin-resistant Staphylococcus aureus (48.5%, 28.3%, 17.1%) and P. aeruginosa (27.3%, 17.4%, 29.3%) were more frequently identified pathogenic organisms. Nosocomial infection reduced from 26.2%/2015 to 13.6%/2017. Essential bacteria of nosocomial infection from 2015 to 2017 following time methicillin-resistant Staphylococcus aureus (31.8%; 45.5% and 36.4%) and P. aeruginosa (68.1%, 81.8% and 45.5%). There was no relationship between nosocomial infection and age, sex, type disease, diabetes in pemphigus patients. The rate of methicillin-resistant Staphylococcus aureus resistanced with penicilline, clindamycin, erythromycin, cefoxitin were not changed since 2015 - 2017. Conclusion: Pemphigus patients had very hight infection at the hospitalised time, more frequently with S. aureus, methicillin-resistant Staphylococcus aureus and P. aeruginosa. Essential bacteria of nosocomial infection were methicillin-resistant Staphylococcus aureus and P. aeruginosa and it is recommended the antimicrobial resistance be taken into notice.
Keywords: Pemphigus, nosocomial infection, antimicrobial resistance.
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References
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