ISSN: 1859 - 2872
Early results of combined navigation guided drainage surgery with alteplase in treatment of spontaneous supratentorial intracerebral hemorrhage
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Abstract
Objective: To evaluate results of navigation guided drainage surgery in combination with ateplase for spontaneous supratentorial intracerebral haemorrhage at hospital discharge. Subject and method: A prospective study of 80 cases spontaneous supratentorial intracerebral haemorrhage underwent frameless stereotactic aspiration the hematoma plus alteplase at 108 Military Central Hospital. Average age was 55.6 ± 11.4 (28-80), male/female was 4/1. Bleeding in the basal ganglia - thalamus was 73.7%. The mean hospital stay was 14.8 ± 5.7 days. Result: Conscious status at hospital discharge (Glasgow score) improved compared to preoperative (10.9 vs 8.9, p<0.05); hematoma volume decreased from 71.9 to 23.9ml; midline shift decreased from 10.6 to 5.6mm (p<0.01). Factors related to the state of consciousness at discharge include: Preoperative Graeb score (r = -0.34, p<0.01), postoperative residual hematoma volume (r = -0.49), p<0.01), degree of midline shift (r = -0.4, p<0.01) and Graeb score at discharge (r = -0.49, p<0.01). Conclusion: Navigation guided drainage surgery in combination with ateplase improved the clinical status according to the Glasgow scale, reduced hematoma volume, midline shift and Graeb score. The smaller the remaining hematoma volume, the better the patient's improvement.
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References
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