ISSN: 1859 - 2872
Features of corticospinal tract in diffusion tensor imaging of 25 Vietnamese Alzheimer patients
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Abstract
Objective: To reconstruct the characteristics of corticospinal tract (CST) in Vietnamese Alzheimer patients (AD) by using Diffusion tensor imaging (DTI). Subject and method: A cross-sectional study. We reconstructed the white matter (WH) fibers of CST of 25 Vietnamese Alzheimer patients using DTI. Result: The mean (± SD) age of AD patient was: 68.64 ± 7.90, the max age was: 84 years, the min age was: 56 years; Male/female: 10/15, the mean (±SD) age of male/female was: 66.60 ± 8.09/70.00 ± 7.74 years, no significant difference between male and female (p=0.30). The mean (±SD) number and length of fibers, voxel, ADC of CST in both sides (right and left) were: 238.84 ± 130.68 fibers and 228.00 ± 108.92 fibers; 109.44 ± 17.57mm and 110.34 ± 18.74mm; 484,.24 ± 151.48 voxels and 516.20 ± 188.46 voxels; 0.89 ± 0.13 and 0.86 ± 0.14, no significant difference (p>0,05). The mean (±SD) FA of CST in both sides (right and left): 0.47 ± 0.03 and 0.48 ± 0.03, a significant difference: p=0.005. Conclusion: The results suggest that: Reconstructing CST by using DTI would have potential benefits in demonstrating the abnormal of white matter integrity in Vietnamese AD patients. More comparative studies with healthy subjects are needed.
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References
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