Rối loạn lipid máu ở bệnh nhân đái tháo đường typ 2 có biến chứng thận

Abstract

Objective: Learn the characteristics of dyslipidemia in patients with type 2 diabetes with renal complications and related factors. Subject and method: 60 patients with type 2 diabetes mellitus with renal complications. Cross-sectional descriptive study on 60 patients. Result: 31 male patients (51.7%), 29 female patients (48.3%). Average age: 59.2 ± 9.7. Highest cholesterol  total  in the age group  ≥ 70, highest triglycerides in the age group 50 - 59, LDL-C was highest in the age group 39 - 49. 50% increased cholesterol; 41.7% hypertriglyceridemia; 46.6% increased in LDL-C; 43.3% decreased in HDL-C. 31.7% of patient had a disorder of blood lipid 1 components; 20% of patients with high cholesterol  total and triglycerides, 23.3% of patients with high cholesterol total and LDL-C, 13.3% of patients increased in both cholesterol total, triglyceride and LDL-C. There were differences in the levels of  total cholesterol, HDL-C, LDL-C in the groups with different levels of urinary protein. LDL-C inversely correlated with urea, albumin, GRF (r = -0.29; -0.3; -0.38, p<0.05). Cholesterol total positive correlated with HbA1C (r = 0.29, p<0.05). Conclusion: 31.7% of patients with disorders of only one lipid components, 43.3% lipid disorders 2 components; 13.3% lipid disorders 3 components. There was a negative correlation between LDL-C with urea, albumin, GRF and a positive correlation between total cholesterol with HbA1C statistically significant (p<0.05).