Extract and isolated compounds from the leaves of Murdannia bracteata (C.B.Clarke) J.K.Morton ex D.Y.Hong

  • Manh Nguyen Hung Học viện Quân y
  • Mến Chu Van Học viện Quân y
  • Loi Vu Duc Trường Đại học Quốc gia Hà Nội
  • Linh Tran Xuan Bệnh viện Quân y 4

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Keywords

Daucosterol, acid tricosanoic, acid montanic, stigmasterol acid betulinic

Abstract

Objective: Extract, isolate and determine the structure of some compounds from leaves of Murdannia bracteata. Subject and method: Leaf parts of Murdannia bracteata tree collected in Nam Dinh (Vietnam), extracted, isolated compounds, identified structure of isolated substances. Result and conclusion: From the ethanol 80% extract of the leaves of Murdannia bracteata, five compounds (1 - 5) were isolated by chromatographic methods. These isolates were identified daucosterol (HB1), acid tricosanoic (HB2), acid montanic (HB3), stigmasterol (HB4), acid betulinic (HB5) by spectroscopic analyses and comparison with literature data.

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References

1. Trần Thị Hiền (2014) Nghiên cứu các xanthanolid và các thành phần hóa học khác của cây Ké đầu ngựa (Xanthium strumarium L., asteraceae) mọc ở Hà Nội. Luận văn Thạc sĩ khoa học, Trường Đại học Khoa học Tự nhiên - Trường Đại học Quốc gia Hà Nội, Hà Nội.
2. Tôn Nữ Liên Hương, Nguyễn Duy Tuấn (2012) Thành phần hóa học của vỏ cây bằng lăng nước (Lagerstroemia speciosa) thuộc chi tử vi (Lagerstroemia). Tạp chí Khoa học, 22b, tr. 184-189.
3. Cayme JMC, Ragasa CY (2004) Structure elucidation of β-stigmasterol and β-sitosterol from Sesbania grandiflora (Linn.) Pers. and β-carotene from Heliotropium indicum Linn. by NMR spectroscopy. KIMIKA 20(1/2): 5-12.
4. Chaturvedula VSP, Prakash I (2012) Isolation of stigmasterol and β-sitosterol from the dichloromethane extract of Rubus suavissimus. International Current Pharmaceutical Journal 1(9): 239-242.
5. Khan R, Khanam Z, Khan AU (2012) Isolation and characterization of n-octacosanoic acid from Viburnum foetens: A novel antibiofilm agent against Streptococcus Mutans. Med Chem Res 21: 1411-1417.
6. Kwon HC, Min YD, Kim KD (2003) A new acylglycosyl sterol from quisqualis fructus. Arch Pharm Res 26(4): 275-278.
7. Mohamad H, Jamil WANWA, Abas F et al (2009) Octacosanoic acid, long chains saturated fatty acid from the marine sponges Xestospongia sp. Pertanika J. Trop. Agric. Sci 32(1): 51-55.
8. Ooi KL, Loh SI, Tan ML et al (2015) Growth inhibition of human liver carcinoma HepG2 cells and α-glucosidase inhibitory activity of Murdannia bracteata (C.B.Clarke) Kuntze ex J.K. Morton extracts. Journal of Ethnopharmacology 162: 55-60.
9. Sultana N, Afolayanz AJ (2007) A novel daucosterol derivative and antibacterial activity of compounds from Arctotis arctotoides. Natural Product Research 21(10): 889-896.
10. Voutquenne L, Lavauda C, Massiot G et al (1999) Cytotoxic polyisoprenes and glycosides of long-chain fatty alcohols from Dimocarpus fumatus. Phytochemistry 50: 63-69.
11. Wang GJ, Chen SM, Chen WC et al (2007) Selective inducible nitric oxide synthase suppression by new bracteanolides from Murdannia bracteata. Journal of Ethnopharmacology 112: 221-227.
12. Yam MF, Ang LF, Lim CP et al (2010) Antioxidant and hepatoprotective effects of Murdannia bracteata methanol extract. Journal of Acupuncture and Meridian Studies 3(3): 197-202.