Patient-ventilator synchronization in neurally adjusted ventilatory assist and pressure support ventilation

  • Phuc Nguyen Duc Bệnh viện Hữu nghị Đa khoa Nghệ An
  • Binh Nguyen Gia Bệnh viện Bạch Mai
  • Tuyet Le Thi Diem Bệnh viện Bạch Mai
  • Co Dao Xuan Bệnh viện Bạch Mai

Main Article Content

Keywords

Neurally adjusted ventilatory assist, weaning from mechanical ventilation

Abstract

Objective: Determined total of patient-ventilator synchronization in neurally adjusted ventilatory assist (NAVA) and pressure support ventilation (PSV). Subject and method: 65 patients at the Bach Mai Hospital’s ICU were enrolled in the randomized control trial from the 1st of October 2015 to 30th of October 2017, in which 33 patients were mechanically ventilated by NAVA and 32 patients were on PSV. Result: Asynchronization index in the NAVA group was significantly lower than that of PSV group, 8.54 ± 4.63 compared to 11.85 ± 6.42 (p<0.001). NAVA helped reduce the total numbers of asynchronization event, 2.21 ± 1.0 comparing to 2.95 ± 1.57 (p<0.001). Ineffective breathing attempts in the NAVA and the PSV groups were 0.21 ± 0.16 and 0.19 ± 0.2 (p>0.05) respectively. Auto-triggers in NAVA was 0.34 ± 0.19 while that in PSV was 0.28 ± 0.28, (p>0.05). Double triggers was higher in NAVA (1.27 ± 0.65 versus 0.37 ± 0.29, p<0.001). What is more, premature cycling and delayed cycling in NAVA were significantly lower (0.21 ± 0.19 compared to 1.38 ± 0.6, p<0.001), and 0.23 ± 0.33 compared to 1.38 ± 0.6, p<0.001). Conclusion: NAVA increased patient-ventilator synchronization.

Article Details

References

1. Bộ Y tế (2014) Hướng dẫn quy trình kỹ thuật chuyên ngành Hồi sức - Cấp cứu và Chống độc. Nhà xuất bản Y học, tr. 105-114.
2. Thille AW, Rodriguez P, Cabello B et al (2006) Patient-ventilator asynchrony during assisted mechanical ventilation. Intensive Care Med 32(10): 1515-1522.
3. Garzando M, Ferrandis R, Garrigues B et al (2014) Neurally adjusted ventilatory assist: An update. Trends in Anaesthesia and Critical Care 4(4): 115-118.
4. Piquilloud L, Vignaux L, Bialais E et al (2011) Neurally adjusted ventilatory assist improves patient–ventilator interaction. Intensive Care Med 37(2): 263–271.
5. Olivier L, Laure C, Fanny Vardon B et al (2019) Neurally adjusted ventilatory assist (NAVA) versus pressure support ventilation: patient-ventilator interaction during invasive ventilation delivered by tracheostomy. Critical Care 23(1). doi:10.1186/ s13054-018-2288-2
6. Terzi N, Pelieu I, Guittet L et al (2010) Neurally adjusted ventilatory assist in patients recovering spontaneous breathing after acute respiratory distress syndrome: Physiological evaluation. Critical Care Medicine 38(9): 1830.