Role of pancreatic stent in preventing complications of acute pancreatitis after ERCP when impacting the pancreatic duct

  • Thái Doãn Kỳ Bệnh viện Trung ương Quân đội 108
  • Phạm Minh Ngọc Quang Bệnh viện Trung ương Quân đội 108
  • Nguyễn Thị Huế Bệnh viện Trung ương Quân đội 108
  • Lê Thị Thuận Bệnh viện Trung ương Quân đội 108
  • Bùi Thị Ánh Bệnh viện Trung ương Quân đội 108
  • Phạm Thị Trang Bệnh viện Trung ương Quân đội 108
  • Mai Thanh Bình Bệnh viện Trung ương Quân đội 108

Main Article Content

Keywords

Acute Pancreatitis, complications post endoscopic retrograde cholangiopancreatography, pancreas stent placement

Abstract

Objective: To evaluate the role of pancreatic stent placement in preventing post-ERCP acute pancreatitis when the pancreatic duct is manipulated. Subject and method: A retrospective study of 298 patients who underwent ERCP to treat biliary obstruction or cholangitis with pancreatic duct manipulation (contrast injection or guidewire placement) at 108 Military Central Hospital from January 2021 to March 2024. Patients were divided into two groups: no pancreatic stent placement (128 patients) and pancreatic stent placement (170 patients). Result: There were no significant differences in age and gender between the two groups. Pancreatic stent placement was strongly associated with a reduced risk of post-ERCP acute pancreatitis (incidence of acute pancreatitis in patients without vs. with pancreatic stent placement: 41.2% vs. 21.9%; OR = 0.4, p=0.0005). Among patients with elevated pancreatic enzymes after ERCP, stent placement significantly reduced the risk of progression to acute pancreatitis (OR = 0.17, p<0.0001). The incidence of other complications, such as post-sphincterotomy bleeding, infection, and perforation, was similar between the two groups. Pancreatic stent migration was rare (0.8%). Conclusion: Pancreatic stent placement is an effective and safe measure for preventing post-ERCP acute pancreatitis in high-risk patients, reducing complications and improving treatment outcomes.

Article Details

References

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