Some clinical-pathological characteristics and factors related to muscle-invasion in newly diagnosed bladder cancer

Tóm tắt

Objective: To learn about some clinical and histological characteristics of bladder cancer, as well as investigate about some factors related to muscle-invasion in newly diagnosed bladder cancer. Subject and method: A descriptive retrospective study was conducted on 416 patients with newly diagnosed bladder cancer who underwent transurethral resection of bladder tumor within 6 years from 2018 to 2023 at 108 Military Central Hospital. Result: Mean age was 66.3 ± 12.4 (16-92); male 88.7%, female 11.3%; male/female ratio was 7.8/1. Asymptomatic gross hematuria was the majority (77.9%). Papillary tumors were the majority (62.3%), commonly found in both lateral walls (53.6%), most were ≤ 3cm in size (72.8%), and more than half of the patients had a solitary tumor (54.3%). Most bladder cancers were urothelial carcinomas (99.04%), of which 76.9% were high-grade malignancy; the rate of non-muscle-invasive tumors detected for the first time was 76.9%. The rate of muscle-invasive tumors in both sexes was similar; meanwhile, advanced age, sessile tumor characteristics, tumor size > 3cm, number > 3 tumors, and high-grade malignancy were all statistically significant factors related to muscle-invasive tumors. Conclusion: The detection rate of the first diagnosed non-muscle-invasive bladder cancer was comparable to the world literature; some tumor characteristics were statistically significantly associated with the presence of muscle-invasive tumor.