ISSN: 1859 - 2872
Preliminary evaluation of 18FDG PET findings in pediatric patients with autism
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Objective: The purpose of this study was to evaluate 18FDG positron emission tomography (PET) findings in pediatric patients with autism. Subject and method: This study includes 15 autism pediatric patients who were diagnosed at the Vinmec International Hospital from January 2017 to May 2017 and five oncology patients without neurology’s diseases underwent to whole body PET scan (from vertex to midthigh) were selected as control group. All patients underwent PET/CT brain examination in Nuclear Medicine Department, 108 Military Central Hospital. Result: Mean patient age (7.1 ± 0.24). On the PET scans of the 15 patients with autism, 13 (86%) had significantly decreased metabolic activity of both hemispheres. All of the patients had decreased metabolism in temporal, parietal and cingulate gyrus. Mean of Z-scores of autism group showed significantly decreased activity in comparison with Z-score of the control group. There were relations between clinical and grade of hypometabolism of autism. Conclusion: Hypometabolism in the brain of autism pediatric patients may present a role in diagnosis and prognosis.
Keywords: Autism, 18FDG PET.
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Các tài liệu tham khảo
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