Outcomes of treatment in patients with bacteria of secondary sepsis from cholestasis
Main Article Content
Keywords
Abstract
Objective: To characterize outcomes of treatment in patients with bacteria of secondary sepsis from cholestasis. Subject and method: We conducted a prospective study of 38 patients with secondary sepsis from cholestasis at the 108 Military Central Hospital from January 2020 to August 2020. Using BACTEC 9020 machine of Becton Dickinson - USA and identification of bacteria by Bio Merieux's Vitex II Compact system - France to determine the agent causing sepsis. Or PCR-based Sepsis@Quick test is for identifcation of sepsis-causative pathogens. Result: Men (63.2%) was higher than women (36.8%). The mean age was 64.8 ± 12.7 years. Sepsis-causative pathogens: Escherichia coli (55.3%); Klebsiella pneumoniae (31.6%). Period of treatment in hospital from 15 to 21 days accounted for the highest rate of 39.5%, followed by 8 - 14 days, accounting for 34.2%. Aminoglycoside group (86.8%) and beta lactam group (84.2%) were used more than other groups. The patient received primary medical treatment (60.5%), followed by ERCP (36.8%). Patients who have recovered from the disease accounted for a high rate (89.5%), the number of deaths accounted for a low rate (5.3%). Conclusion: Patients receive mainly medical treatment. Using aminoglycoside and beta lactam groups is appropriate, leading to a shortened hospital stay and a high proportion of cases of cure.
Article Details
References
2. Đỗ Hữu Liệt và cộng sự (2014) Phẫu thuật triệt để ung thư đường mật vùng rốn gan: 38 trường hợp. Tạp chí Nghiên cứu Y học thành phố Hồ Chí Minh, Tập 18, Phụ bản của Số 2.
3. Hà Văn Mạo, Vũ Bằng Đình (2009) Bệnh học gan mật tụy. Nhà xuất bản Y học, tr. 772-789.
4. He-Bin Fan, Dong-Liang Yang, An-Shen Chen (2013) Sepsis-associated cholestasis in adult patients: A prospective study. J Med Sci 346(6): 462–466
5. Richard H Moseley (2004) Sepsis and cholestasis. Clin Liver Dis 8: 83-94.
6. Kubler A, Adamik B, Ciszewicz-Adamiczka B et al (2015) Severe sepsis in intensive care units in poland a point prevalence study in 2012 and 2013. Anaesthesiol Intensive Ther 47(4): 315-319.
7. Nisha Chand and Arun J Sanyal (2007) Sepsis-induced cholestasis. Hepatology 45(1): 230-241.
8. Phua J, Koh Y, Du B (2011) Management of severe sepsis in patients admitted to Asian intensive care units: prospective cohort study. BMJ 342: 3245.
9. Wang E, Szychowski M, Griffin R et al (2014) Long-term mortality after community-acquired sepsis: A longitudinal population-based cohort study. BMJ 4(1): 004283.