Outcomes of treatment in patients with bacteria of secondary sepsis from cholestasis

  • Le Thi Thu Hien Thai Nguyen University of Medicine and Pharmacy
  • Dong Duc Hoang Thai Nguyen University of Medicine and Pharmacy

Main Article Content

Keywords

Outcomes, treatment, bacteria, sepsis, cholestasis

Abstract

Objective: To characterize outcomes of treatment in patients with bacteria of secondary sepsis from cholestasis. Subject and method: We conducted a prospective study of 38 patients with secondary sepsis from cholestasis at the 108 Military Central Hospital from January 2020 to August 2020. Using BACTEC 9020 machine of Becton Dickinson - USA and identification of bacteria by Bio Merieux's Vitex II Compact system - France to determine the agent causing sepsis. Or PCR-based Sepsis@Quick test is for identifcation of sepsis-causative pathogens. Result: Men (63.2%) was higher than women (36.8%). The mean age was 64.8 ± 12.7 years. Sepsis-causative pathogens: Escherichia coli (55.3%); Klebsiella pneumoniae (31.6%). Period of treatment in hospital from 15 to 21 days accounted for the highest rate of 39.5%, followed by 8 - 14 days, accounting for 34.2%. Aminoglycoside group (86.8%) and beta lactam group (84.2%) were used more than other groups. The patient received primary medical treatment (60.5%), followed by ERCP (36.8%). Patients who have recovered from the disease accounted for a high rate (89.5%), the number of deaths accounted for a low rate (5.3%). Conclusion: Patients receive mainly medical treatment. Using aminoglycoside and beta lactam groups is appropriate, leading to a shortened hospital stay and a high proportion of cases of cure.

Article Details

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