Tăng sản tế bào vảy ở thực quản: Triệu chứng lâm sàng, hình ảnh nội soi và mô bệnh học

Abstract

Objective:  To review the patients who were diagnosed with glycogenic acanthosis on upper gastrointestinal endoscopy and to describe the clinical symptoms, endoscopic and pathological features. Subject and method: A total of 67 patients who underwent upper gastrointestinal endoscopy and then biopsy for evaluation of squamous hyperplasia and other lesions from 8/2020 to 12/2020 in 108 Military Central Hospital. Result:  Squamous epithelium. Esophgeal squamous hyperplasia was detected in 67 patients. Among them, 55 were male (82.1%) and 12 were female (17.9%). Patients with glycogenic acanthosis were aged 38 - 84 years, average 61.5 ± 9.3 years. The most common symptoms were heartburn 53(79.1%), belching and bloating 52 (77.6%), upper central abdominal pain 59 (88.1%). The less common symptoms were chronic cough 18 (26.9%), difficulty swallowing 2 cases (3.0%). Gastroesophageal reflux was detected in 57 cases (85.1%) with squamous hyperplasia, while hiatal hernia was detected in 3 (4.5%) cases. Clinically, mild glycogenic acanthosis was a common finding, in 55 (82.1%) cases. Pathologically, benign squamous hyperplasia was 65 cases (97.0%), and with dysplasia squamous epithelium was 2 patients (3.0%). Conclusion: The common clinical symptoms areabdominal pain, burning, bloating and belching. Endoscopically, 81.2% of them with moderate degree of squamous cell hyperplasia. The main accompanying endoscopic lesions are GERD and gastritis. Histopathologically, most cases are benign squamous hyperplasia; squamous cell dysplasia is observed in 3% of cases.