ISSN: 1859 - 2872
Evaluation of the results of laparoscopic surgery for rectal cancer after preoperative long-course chemoradiotherapy treatment
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Abstract
Objective: To evaluate the results of laparoscopic surgery for rectal cancer after preoperative long-course chemoradiotherapy. Subject and method: A prospective descriptive study in 235 rectal cancer patients treated with preoperative long-course chemoradiotherapy and laparoscopic surgery at 108 Military Central Hospital from January 2018 to August 2020. These patients were re-evaluated at least 6 weeks after the end of long-course chemoradiotherapy. Assessment of response to clinical and subclinical symptoms before surgery, results of response to disease stage on pathology and results of laparoscopic rectal surgery. Result: The clinical response rate was 82.9%, with 17.8% fully response. The rate of anal sphincter preserving was 84.3%. The rate of laparoscopic lateral pelvic lymph node dissection was 8.1%, of which 21.1% patients had lateral pelvic lymph node metastasis. The rate of postoperative complications was 11.6%. Response assessment on pathology: Reducing the degree of tumor invasion (T) 89.8%, reducing the degree of spread to regional lymph nodes (N) 75.3%. Side effects after long-course chemoradiotherapy were mainly in grade 1 and 2. Conclusion: Laparoscopic surgery treatment for rectal cancer after receiving preoperative long-course chemoradiotherapy was safe and effective. Preoperative long-course chemoradiotherapy reduces the disease stage with less toxicity, and increase the rate of sphincter preservation when combined with laparoscopic surgery.
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References
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