The clinical and neuroimaging characteristics in acute ischemic stroke patients with intracranial and extracranial arterial stenosis in Phu Tho General Hospital

  • Nguyen Thi Thanh Mai Phu Tho Hospital
  • Nguyen Huy Ngoc Phu Tho Hospital
  • Nguyen Hong Quan 108 Military Central Hospital
  • Nguyen Van Thong 108 Military Central Hospital

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Keywords

Nhồi máu não, vữa xơ động mạch, kháng tiểu cầu kép

Abstract

Objective: To investigate several clinical and neuroimaging characteristics in acute ischemic stroke patients with intracranial and extracranial arterial stenosis in Phu Tho General Hospital. Subject and method: A cross-sectional descriptive prospective study on 102 ischemic stroke patients hospitalized within 72 hours from the onset, with mild and moderate severity (NIHSS ≤ 15), were treated in Phu Tho General Hospital from September 2015 to October 2018. Result and conclusion: The proportion of male patients accounted for 60.8%, higher than female ones, the group of 60 - 69 years old patients accounted for the highest proportion of 42%. The most common risk factor related to ischemic stroke were hypertension (81.4%), smoking (56.9%), diabetes mellitus 42% and lipid disorders (37%). The most common onset symptoms were hemiparesis 90%, hemisensory deficits (88.2%), cranial nerve lesions (80.4%)... To evaluate stenosis and occlusive of intracranial arteries on MRA, a stenosis artery (96.2%), multiple stenosis arteries (3.8%); mild stenosis 29.6% and occlusive 40.7%. To evaluate stenosis and occlusive of extracranial arteries on carotid Doppler ultrasound, a stenosis artery (63.8%), multiple stenosis arteries (36.2%); mild stenosis 53.1% and occlusive 1.6%.

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References

1. Nguyễn Văn Thông, Hoàng Văn Thuận (2013) Bệnh học thần kinh. Nhà xuất bản Y học, tr. 83.
2. Lê Đình Toàn (2016) Nghiên cứu đặc điểm lâm sàng, hình ảnh hẹp, tắc động mạch ở bệnh nhân nhồi máu động mạch não giữa trên phim chụp cộng hưởng từ mạch 3 Tesla. Luận án Tiến sĩ.
3. Nguyễn Văn Thông, Đinh Thị Hải Hà, Nguyễn Hồ̀ng Quân (2012) Nhận xét đặc điểm, tính chất, cơ cấu bệnh tật tại trung tâm Đột quỵ - Bệnh viện Trung ương Quân đội 108 từ tháng 1/2003 đến tháng 6/2012. Tạp chí Y Dược lâm sàng 108 7 (10/2012), tr. 10-21.
4. Chimowitz MI, Lynn MJ, Howlett-Smith H et al (2005) Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 352(13): 1305-1316.
5. Mundiyanapurath S et al (2016) Posterior circulation acute stroke prognosis early computed tomography score using hypointense vessels on susceptibility weighted Imaging Independently Predicst Outcome in patienst with basilar artery occlusion. PloS one 10(7): e0132587.
6. Ferguson GG et al (1999) The North American symptomatic carotid endarterectomy trial: Surgical results in 1415 patients. Stroke 30(9): 1751-1758.
7. Thorleif E et al (2014) Detection of acute brainstem infarction by using DWI/MRI. Neurological Differential Diagnose.
8. Wang Y, Zhao X, Liu L et al (2014) Prevalence and outcomes of symptomatic intracranial large artery stenoses and occlusions in China: The Chinese intracranial atherosclerosis (CICAS) study. Stroke 45(3): 663-669.
9. William JP, Alejandro AR et al (2019) Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke. Stroke 50: 344-418.
10. Aboyans V, Ricco JB, Bartelink MEL et al (2017) 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries Endorsed by: The European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS). Eur Heart J 39(9): 763-816.