Nghiên cứu kết quả dẫn lưu nang giả tụy qua dạ dày tá tràng dưới hướng dẫn siêu âm nội soi

Abstract

Objective: To evaluate the successful rate, efficacy and complications of EUS–guided pancreatic pseudocyst (PPC) drainage at Cho Ray Hospital. Subject and method: Prospective, uncontrolled intervention study all of patients underwent EUS-guided PPC drainage in Cho Ray Hospital from January 2016 to August 2019. Technical success was defined as the ability to access and drain the pseudocysts by the placement stents. Treatment success was defined as complete resolution or decrease in the size of PPC (complete resolution or the size of cyst < 50% or ≤ 2cm) on follow-up imaging, together with resolution of symptoms. Follow up and evaluation of treatment were assessed at one to three months, after three to six month, and over six moth after procedure. Complications were assessed in the first week (early complications), and after one week procedure (late complications). Result: Of 60 patients were diagnosed as pancreatic pseudocysts and underwent EUS-guided drainage, the technical success rate was 96.7%. The successful drainage rate was 96.5%. Procedure-related complications were encountered in 7 patients (11.7%) including bleeding in 2 patients, cyst infection in 4 patients and 1 patient had migrated stent into the pseudocyst. Complications of bleeding were mild and self-limiting. The infectious complications were successfully managed by antibiotic therapy in two patients and another two patients needed percutaneous drainage, the migration stent in the cyst needed operate to drainage and removed stent. EUS-guided drainage was not achievement in two patients that were operated cystjejunostomy and percutaneous drainage. The recurrence rate after the first successful drainage was 6.9% (4/58 patients). Conclusion: The results of our study show that the technical success rate was 96.7%, the successful drainage rate was 96.5%, the complication rate was 11.7% and the recurrence rate was 6.9%. EUS-guided pancreatic pseudocyst drainage is considered to have high technical success rate, effectiveness and safety.