ISSN: 1859 - 2872
The correlation between plasma CK-MB concentration and the QRS axis changes in patients with acute myocardial infarction following primary coronary intervention
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Abstract
Objective: To evaluate the correlation between the plasma CK-MB concentration and the change in the QRS axis in patients with acute myocardial infarction following percutaneous coronary artery intervention. Subject and method: A retrospective study on 89 acute myocardial infarction patients receiving percutaneous coronary intervention at 108 Military Central Hospital from April 2018 to April 2019. The axis of the QRS complex is calculated by the formula based on leads D1 and D3. Myocardial infarction area size is determined by the concentration of creatinine kinase (CK-MB). Result: 89 patients included in the study had an average age of 68.5 ± 9.1 years, the majority was male (83.1%). 51.1% of hospitalized patients with non-ST elevation myocardial infarction, 35.1% had the ST elevation myocardial infarction. Unidentified myocardial infarction area on the electrocardiogram is 49% and majority had left anterior coronary artery blockage (51.7%). The correlation between the changes in the ECG axis and CKMB biomarker was weak (r = 0.043) and statistically insignificant (p>0.05). Subgroup analysis showed a moderate correlation between changes in alpha angle and CKMB enzymes in patients with left anterior descending artery infarction. Conclusion: The ECG axis or the axis of QRS complex gets little clinical attention. However, the QRS axis can be considered a predictor of the size of myocardial infarction area due to occlusion of left descending coronary artery
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References
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