Value of cystatin C for early detection of acute kidney injury after cardiac surgery

  • Trung Ngo Dinh Bệnh viện Trung ương Quân đội 108
  • Tot Nguyen Hong Bệnh viện Trung ương Quân đội 108
  • Thach Nguyen Cam Bệnh viện Trung ương Quân đội 108
  • Hinh Quach Xuan Bệnh viện Trung ương Quân đội 108
  • Anh Tran Duy Bệnh viện Trung ương Quân đội 108

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Keywords

Acute kidney injury, cardiac surgery, cystatin C

Abstract

Objective: To assess whether cystatin C could early detect of acute kidney injury (AKI) after cardiac surgery. Subject and method: A prospective, descriptive study on 247 patients underwent cardiac surgery with cardiopulmonary bypass in the 108 Military Central Hospital from January 2015 to September 2017. AKI was diagnosed by KDIGO criteria. Serum cystatin C was measured at the following times: Arrival in ICU (T1), 24 hours (T2), and 48 hours later (T3) and compare with serum creatinin at the same times. Result: Among 247 patients, AKI was detected in 48.58%. Cystatin C had a strong corelation with serum creatinin. At T1, cystatin C had AUC = 0.73, 95% CI: 0.64 – 0.82, better than that of creatinin (AUC = 0.66, 95% CI: 0.56 – 0.76). Conclusion: Serum cystatin C, measured when arrival in ICU can early detect of AKI in patients with cardiac surgery.

Article Details

References

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Published
Aug 14, 2019
Issue
Volume 14 - No 5/2019
Section
Articles
How to Cite
Ngo DinhT., Nguyen HongT., Nguyen CamT., Quach XuanH., & Tran DuyA. (2019). Value of cystatin C for early detection of acute kidney injury after cardiac surgery. Tạp Chí Y Dược lâm sàng 108, 14(5). Retrieved from https://tcydls108.benhvien108.vn/index.php/YDLS/article/view/93