Đặc điểm lâm sàng, cận lâm sàng bệnh do cầu khuẩn màng não xâm nhập tại các đơn vị Quân đội từ 2014 đến 2021

Abstract

Objective: To describe clinical, subclinical characteristics of invasive meningococcal disease in military units from 2014 to 2021. Subject and method: A cross-sectional and restrospective study, patients were military staffs with septicemia/meningococcal meningitis classified using the case determination criteria of the Ministry of Health. Result and conclusion: 69 cases with invasive menigococcal disease were recorded with 74.6% of the cases were soldiers enrolled < 1 year. The overall mortality rate was 8.69%. The classical symptoms: Purpura (58.6%); neck stiffness (77.9%); mostly observed at the 20^th hour from symptom onset. Severe symptoms: Shock, coma, convulsions were observed in 29.4%, 25% and 16.2% of the cases, respectively. Blood test: 95.7% with increased WBC (mean 22.4 ± 8.6G/L); 100% with increased procalcitonin, 37.7% with Thrombocytopenia; 67.9% with decreased Prothrombin time. Cerebrospinal fluid test: Cloudy (84.2%), cell count > 1000 (72.6%), mean protein: 2.69 (± 2.48) g/L, low glucose level: 80%. Invasive menigococcal disease remains a health thread in military especially in new recruits.