Clinical experiences in diagnosis and treatment of infective endocarditis patients were treated at the Department of Cardiology, 108 Miltitary Central Hospital, from 2015 to 2020

  • Đỗ Văn Chiến Bệnh viện Trung ương Quân đội 108
  • Nguyễn Dũng Bệnh viện Trung ương Quân đội 108
  • Lê Minh Hiếu Bệnh viện Trung ương Quân đội 108

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Keywords

Endocarditis, experience, antibiotics

Abstract

Objective: To describe the clinical experiences in diagnosis and treatment of infective endocarditis at the Department of Cardiology, 108 Military Central Hospital from 2015 to 2020. Subject and method: A retrospective, descriptive, cross-sectional study collected patient data based on electronic medical records in 5 years from 2015 to 2020. Result: A total of 42 patients were included in the study with an average age of 49.17 ± 16.71, more men than women (64.3%). The most common lesions were the mitral valve (54.7%), then the aortic valve (26.1%). Blood cultures mainly showed Streptococci (38.1%), or negative (28.1%), Staphylococci (11.9%). Antibiotics were mainly used in combination of 2 types (64.3%), 3 types (14.3%) of which the main combination was vancomycin (50.0%), quinolone (45.2%) and cephalosporins (41.3%). The majority of patients received planned surgery in 6 months (57.1%), or conservative treatment (33.3%). The 6-month mortality rate for this group was 9.5%. Conclusion: Infective endocarditis is a complex disease with high morbidity and mortality rates.

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References

Wallace SM et al (2002) Mortality from infective endocarditis: Clinical predictors of outcome. Heart (British Cardiac Society) 88(1): 53-60.
2. Mylonakis E and Calderwood SB (2001) Infective endocarditis in adults. N Engl J Med 345(18): 1318-1330.
3. Habib G et al (2015) 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). European Heart Journal 36(44): 3075-3128.
4. Zhu W, Zhang Q, and Zhang J (2017) The changing epidemiology and clinical features of infective endocarditis: A retrospective study of 196 episodes in a teaching hospital in China. BMC Cardiovascular Disorders 17(1): 113.
5. Rizk HH et al (2019) Clinical features and outcomes of infective endocarditis in Egypt: an 11-year experience at a tertiary care facility. The Egyptian Heart Journal 71(1): 17.
6. Houpikian P and Raoult D (2005) Blood culture-negative endocarditis in a reference center: etiologic diagnosis of 348 cases. Medicine (Baltimore) 84(3): 162-173.